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Home » Two Conditions That Are Often Misdiagnosed as Carpal Tunnel Syndrome
two conditions that are often misdiagnosed as carpal tunnel syndrome
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Two Conditions That Are Often Misdiagnosed as Carpal Tunnel Syndrome

Hours News
Last updated: April 22, 2025 6:04 pm
By Hours News
8 Min Read
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Carpal Tunnel Syndrome (CTS) is one of the most commonly diagnosed nerve disorders, affecting millions worldwide. It occurs when the median nerve, which runs through the carpal tunnel in the wrist, is compressed, leading to symptoms such as numbness, tingling, and pain in the hand and fingers.

Contents
Condition #1: Cervical RadiculopathyWhat Is Cervical Radiculopathy?Overlapping Symptoms with CTSKey Differences from Carpal Tunnel SyndromeDiagnostic TipsCondition #2: Thoracic Outlet Syndrome (TOS)What Is Thoracic Outlet Syndrome?Overlapping Symptoms with CTSKey Differences from Carpal Tunnel SyndromeDiagnostic TipsWhy Misdiagnosis HappensThe Impact of MisdiagnosisGetting the Right DiagnosisFAQConclusion

However, what many don’t realize is that two conditions that are often misdiagnosed as carpal tunnel syndrome shares symptoms with several other conditions. This overlap can result in misdiagnosis and ineffective treatment plans. Among the most frequently confused disorders are Cervical Radiculopathy and Thoracic Outlet Syndrome (TOS).

Condition #1: Cervical Radiculopathy

What Is Cervical Radiculopathy?

Cervical radiculopathy occurs when a nerve root in the cervical spine (neck area) becomes compressed or irritated. This is typically due to a herniated disc, degenerative disc disease, or spinal stenosis. The resulting symptoms can mimic those of carpal tunnel syndrome quite closely.

Overlapping Symptoms with CTS

  • Tingling or numbness in the arm, hand, or fingers
  • Weakness in the shoulder, arm, or hand
  • Pain radiating down from the neck to the fingers
  • Difficulty gripping objects or fine motor skills

These symptoms often lead healthcare providers to suspect CTS, especially if they are not taking a full spinal or neurological history.

Key Differences from Carpal Tunnel Syndrome

  • Location of pain: While CTS pain usually starts in the wrist and fingers (especially the thumb, index, and middle fingers), cervical radiculopathy pain often begins in the neck or shoulder and travels downward.
  • Muscle weakness patterns: In cervical radiculopathy, muscle weakness may be more diffuse and include muscles in the upper arm and shoulder, not just the hand.
  • No wrist compression: CTS is due to compression of the median nerve at the wrist, while cervical radiculopathy involves nerve roots in the neck.

Diagnostic Tips

Electromyography (EMG) and nerve conduction studies can help differentiate between CTS and cervical radiculopathy. A thorough clinical examination and imaging of the cervical spine, such as MRI, may also be necessary.

Condition #2: Thoracic Outlet Syndrome (TOS)

What Is Thoracic Outlet Syndrome?

Thoracic Outlet Syndrome involves compression of nerves and/or blood vessels in the area between your collarbone and first rib, called the thoracic outlet. This can occur due to anatomical abnormalities, trauma, poor posture, or repetitive activity.

Overlapping Symptoms with CTS

  • Numbness or tingling in the hand and fingers
  • Pain in the neck, shoulder, arm, or hand
  • Weak grip or fatigue in the hand
  • Coldness or discoloration in the fingers (in vascular TOS)

Given the similar neurological symptoms, TOS can easily be mistaken for CTS—especially when the median nerve is involved in the compression.

Key Differences from Carpal Tunnel Syndrome

  • Broader symptom area: Unlike CTS, which mainly affects the palm side of the thumb and first few fingers, TOS symptoms often cover the entire arm and may include vascular symptoms such as swelling or discoloration.
  • Positional symptoms: TOS symptoms are often worse with certain arm positions, like overhead reaching or carrying heavy objects.
  • Physical examination findings: Special tests like Adson’s or Roos test can help provoke TOS symptoms but are not typically relevant in CTS diagnosis.

Diagnostic Tips

Diagnosis of TOS can be complex and may require a combination of clinical tests, imaging studies (like Doppler ultrasound or MRI), and ruling out other conditions like CTS. Unlike CTS, TOS is often a diagnosis of exclusion.

Why Misdiagnosis Happens

Several reasons contribute to the misdiagnosis of CTS when other conditions are actually to blame:

  • Symptom similarity: Tingling, numbness, and hand pain are common symptoms in multiple conditions.
  • Limited clinical testing: Some clinicians may rely too heavily on patient-reported symptoms without conducting nerve conduction studies or imaging.
  • Overgeneralization: CTS is widely recognized, so there is a tendency to default to that diagnosis, especially if a patient works in a repetitive-motion job or uses a computer frequently.

The Impact of Misdiagnosis

Being misdiagnosed can lead to:

  • Ineffective treatment: Patients may undergo unnecessary carpal tunnel surgery, wear splints, or take medications that don’t address the actual problem.
  • Worsening condition: Delay in proper diagnosis can cause the real condition (e.g., cervical disc herniation or vascular compression) to worsen, leading to long-term nerve damage.
  • Psychological effects: Chronic pain and frustration from failed treatments can affect a person’s mental health and quality of life.

Getting the Right Diagnosis

If you’re experiencing symptoms commonly associated with carpal tunnel syndrome, it’s essential to:

  • Consult a specialist: Neurologists, orthopedic specialists, or physical medicine doctors can provide more detailed evaluations.
  • Request comprehensive testing: EMG, nerve conduction studies, and MRIs can uncover the actual source of nerve compression.
  • Consider second opinions: If treatments for CTS aren’t working, a second evaluation could uncover the real issue.

Read More: Hoursnews

FAQ

What is the most common condition misdiagnosed as carpal tunnel syndrome?

Cervical radiculopathy is often mistaken for CTS because it can cause similar symptoms like tingling and numbness in the hand.

How can I tell the difference between carpal tunnel syndrome and thoracic outlet syndrome?

CTS symptoms are mostly limited to the hand, especially the thumb, index, and middle fingers, while TOS often affects the entire arm and includes neck and shoulder symptoms, often made worse by certain arm positions.

Can carpal tunnel syndrome be misdiagnosed from a physical exam alone?

Yes, relying solely on physical symptoms without nerve conduction tests or imaging can lead to misdiagnosis.

Are EMG and nerve conduction tests painful?

They may cause mild discomfort but are generally well tolerated. They’re critical for differentiating between CTS and other conditions.

Should I get surgery for carpal tunnel if I’m not getting better?

Only after a confirmed diagnosis via proper testing. If CTS treatments aren’t helping, a reevaluation is important to rule out other conditions like cervical radiculopathy or TOS.

Conclusion

Carpal Tunnel Syndrome may be a familiar diagnosis, but it’s not always the correct one. Cervical radiculopathy and Thoracic Outlet Syndrome are two conditions that share many symptoms with CTS, leading to frequent misdiagnoses.

Understanding the differences between these conditions can help patients and healthcare providers avoid ineffective treatments and reach the right diagnosis faster. If you’re experiencing persistent numbness, tingling, or pain in your hands, don’t hesitate to seek a thorough medical evaluation—it might not be carpal tunnel after all.

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